Article
The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study.
The Lancet. Infectious diseases - 1 May 2017
Imwong Mallika, Suwannasin Kanokon, Kunasol Chanon, Sutawong Kreepol, Mayxay Mayfong, Rekol Huy, Smithuis Frank M, Hlaing Tin Maung, Tun Kyaw M, van der Pluijm Rob W, Tripura Rupam, Miotto Olivo, Menard Didier, Dhorda Mehul, Day Nicholas P J, White Nicholas J, Dondorp Arjen M
Abstract excerpt
BACKGROUND: Evidence suggests that the PfKelch13 mutations that confer artemisinin resistance in falciparum malaria have multiple independent origins across the Greater Mekong subregion, which has motivated a regional malaria elimination agenda. We aimed to use molecular genotyping to assess antimalarial drug resistance selection and spread in the Greater Mekong subregion. METHODS: In this observational study, we...
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