Article

Evolution and expansion of multidrug resistant malaria in Southeast Asia: a genomic epidemiology study

2019-05-17

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> A multidrug resistant co-lineage of Plasmodium falciparum malaria, named KEL1/PLA1, spread across Cambodia c.2008-2013, causing high treatment failure rates to the frontline combination therapy dihydroartemisinin-piperaquine. Here, we report on the evolution and spread of KEL1/PLA1 in subsequent years. <h4>Methods</h4> We analysed whole genome sequencing data from 1,673 P...

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Literature Corpus work: 92ac1329-74e9-5e5f-940b-0502e2ebfed7
DOI: 10.1101/621763

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