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Article

Parkinson's disease and mitophagy: an emerging role for LRRK2.

Biochemical Society transactions - 30 Apr 2021

Singh Francois, Ganley Ian G

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects around 2% of individuals over 60 years old. It is characterised by the loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain, which is thought to account for the major clinical symptoms such as tremor, slowness of movement and muscle stiffness. Its aetiology is poorly understood as the physiological and...

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Identifiers

PMID: 33769432
DOI: 10.1042/BST20190236
PMCID: PMC8106497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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