Article
TERT promoter mutation in sebaceous neoplasms.
Virchows Archiv : an international journal of pathology - 1 Sept 2021
Muñoz-Jiménez María-Teresa, Blanco Leyla, Ruano Yolanda, Carrillo Rosario, Santos-Briz Ángel, Riveiro-Falkenbach Erika, Requena Luis, Kutzner Heinz, Garrido María Concepción, Rodríguez-Peralto José-Luis
Abstract excerpt
TERT promoter (TERTp) mutations widely occur in multiple human neoplasms, and they have been related to different clinicopathological features. To date, this mutation has not been identified in sebaceous tumors. Here, we analyzed TERTp mutations in 91 sebaceous neoplasms (17 adenomas, 45 sebaceomas, and 29 carcinomas). We detected mutations in 26.7% (8 of 29) of sebaceous carcinomas by pyrosequencing and Sanger...
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