Article
TERT promoter mutations in penile squamous cell carcinoma: high frequency in non-HPV-related type and association with favorable clinicopathologic features.
Journal of cancer research and clinical oncology - 1 Apr 2021
Kim Sang Kyum, Kim Jang-Hee, Han Jae Ho, Cho Nam Hoon, Kim Se Joong, Kim Sun Il, Choo Seol Ho, Kim Ji Su, Park Bumhee, Kwon Ji Eun
Abstract excerpt
PURPOSE: Penile carcinoma is a rare malignant neoplasm with a largely unknown molecular pathogenesis. Telomerase reverse transcriptase promoter (TERT-p) mutations have been detected in several types of human malignancies. The aim of this study was to investigate the presence of TERT-p mutations in penile squamous cell carcinomas (SCCs) and their associations with clinicopathologic features. METHODS: In this...
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