Article
TERT promoter mutations in sinonasal malignant melanoma: a study of 49 cases.
Melanoma research - 1 Jun 2015
Jangard Mattias, Zebary Abdlsattar, Ragnarsson-Olding Boel, Hansson Johan
Abstract excerpt
Sinonasal malignant melanoma (SNMM) comprises less than 1% of all melanomas and is located in the nasal cavity and the paranasal sinuses. The majority of SNMMs have unknown underlying oncogenic driver mutations. The recent identification of a high frequency of driver mutations in the promoter of the telomerase reverse transcriptase (TERT) gene in cutaneous melanoma led us to investigate whether these mutations...
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