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Article

RNA virus population diversity, an optimum for maximal fitness and virulence.

The Journal of biological chemistry - 24 Oct 2014

Korboukh Victoria K, Lee Cheri A, Acevedo Ashley, Vignuzzi Marco, Xiao Yinghong, Arnold Jamie J, Hemperly Stephen, Graci Jason D, August Avery, Andino Raul, Cameron Craig E

Abstract excerpt

The ability of an RNA virus to exist as a population of genetically distinct variants permits the virus to overcome events during infections that would otherwise limit virus multiplication or drive the population to extinction. Viral genetic diversity is created by the ribonucleotide misincorpora...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25213864
DOI: 10.1074/jbc.M114.592303
PMCID: PMC4207971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25213864-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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