Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental defects in trisomy 21 and mouse models.

TheScientificWorldJournal - 19 Sept 2006

Delabar Jean Maurice, Aflalo-Rattenbac Revital, Créau Nicole

Abstract excerpt

Aneuploidies have diverse phenotypic consequences, ranging from mental retardation and developmental abnormalities to susceptibility to common phenotypes and various neoplasms. This review focuses on the developmental defects of murine models of a prototype human aneuploidy: trisomy 21 (Down synd...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Congenital heart defects research
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down Syndrome

Share to Gene Dosage

Share to Genomic variations and chromosomal abnormalities

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 17205199
DOI: 10.1100/tsw.2006.322
PMCID: PMC5917200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17205199-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental defects in trisomy 21 and mouse models.PMID 17205199Read ↗

Mouse-based genetic modeling and analysis of Down syndromeSemantic proximity Read ↗

Placental development and function in trisomy 21 and mouse models of Down syndrome: Clues for studying mechanisms underlying atypical developmentSemantic proximity Read ↗

The power of comparative and developmental studies for mouse models of Down syndrome.Semantic proximity Read ↗

Models for Down syndrome: chromosome 21-specific genes in mice.Semantic proximity Read ↗

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes.Semantic proximity Read ↗

Mouse models of aneuploidy to understand chromosome disordersSemantic proximity Read ↗

A non-mosaic humanized mouse model of Down syndrome, trisomy of a nearly complete long arm of human chromosome 21 in mouse chromosome backgroundSemantic proximity Read ↗

Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.Semantic proximity Read ↗

A new mouse model for Down syndrome.Semantic proximity Read ↗

Rodent models in Down syndrome research: impact and future opportunities.Semantic proximity Read ↗

Down syndrome mouse models are looking up.Semantic proximity Read ↗

Mouse models for understanding human developmental anomalies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.