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Concordance in detection of microsatellite instability by PCR and NGS in routinely processed tumor specimens of several cancer types

28 Jun 2023

Abstract excerpt

BACKGROUND: Microsatellite instability (MSI) occurs in several cancer types and is commonly used for prognosis and as a predictive biomarker for immune checkpoint therapy. METHODS: We analyzed n = 263 formalin-fixed paraffin-embedded (FFPE) tumor specimens (127 colorectal cancer (CRC), 55 endometrial cancer (EC), 33 stomach adenocarcinoma (STAD), and 48 solid tumor specimens of other tumor types) with a capillary...

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Cancer Immunotherapy and Biomarkers
Endometrial and Cervical Cancer Treatments
Genetic factors in colorectal cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37376830
DOI: 10.1002/cam4.6293

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