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Article

Partitioned glioma heritability shows subtype-specific enrichment in immune cells.

Neuro-oncology - 2 Aug 2021

Ostrom Quinn T, Edelson Jacob, Byun Jinyoung, Han Younghun, Kinnersley Ben, Melin Beatrice, Houlston Richard S, Monje Michelle, Walsh Kyle M, Amos Christopher I, Bondy Melissa L

Abstract excerpt

BACKGROUND: Epidemiological studies of adult glioma have identified genetic syndromes and 25 heritable risk loci that modify individual risk for glioma, as well increased risk in association with exposure to ionizing radiation and decreased risk in association with allergies. In this analysis, we assess whether there is a shared genome-wide genetic architecture between glioma and atopic/autoimmune diseases....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33743008
DOI: 10.1093/neuonc/noab072
PMCID: PMC8328033

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