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Article

Whole exome sequencing of a gut-associated lymphoid tissue neoplasm points to precursor or early form of sporadic colon carcinoma.

Pathology, research and practice - 1 Apr 2021

Yaseen Alae, Ladenheim Alexander, Olson Kristin A, Libertini Stephen J, McPherson John D, Matsukuma Karen

Abstract excerpt

Gut-associated lymphoid tissue (GALT) carcinoma is a colorectal neoplasm characterized by cystically dilated neoplastic glands that extend into prominent, well-circumscribed submucosal lymphoid tissue. Although often subtle, lamina propria between and around the neoplastic glands (identified by plasma cells, scattered eosinophils, etc.) is frequent in cases with classic morphology, arguing (at least in such...

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Identifiers

PMID: 33740545
DOI: 10.1016/j.prp.2021.153406

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