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Whole-Exome Sequencing Analysis of Inflammatory Bowel Disease-Associated Serrated Dysplasia

13 Jun 2025

Abstract excerpt

The clinicopathologic and molecular features of serrated lesions with dysplasia in inflammatory bowel disease (IBD) remain poorly understood. We examined a total of 2396 patients treated for IBD at the University of Szeged between 2011 and 2023. Among them, 177 (7%) patients were diagnosed with colorectal neoplasia, of which only 11 (6%) had serrated dysplasia (n = 13). Of the 13 lesions, 5 (38%) showed features...

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PMID: 40565166
DOI: 10.3390/ijms26125704

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