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Clinical utility of ABCB1 and ABCG2 genotyping for assessing the clinical and pathological response to FAC therapy in Mexican breast cancer patients.

Cancer chemotherapy and pharmacology - 1 Jun 2021

Turiján-Espinoza Eneida, Ruíz-Rodríguez Víctor Manuel, Uresti-Rivera Edith Elena, Martínez-Leija Ernesto, Zermeño-Nava José de Jesús, Guel-Pañola Arturo, Romano-Moreno Silvia, Vargas-Morales Juan Manuel, Portales-Pérez Diana Patricia

Abstract excerpt

PURPOSE: Resistance to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and cyclophosphamide (FAC) in some patients with locally advanced breast cancer remains one of the main obstacles to first-line treatment. We investigated clinical and pathological responses to FAC neoadjuvant chemotherapy in Mexican women with breast cancer and their possible association with SNPs present in ABC transporters as...

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Antineoplastic Combined Chemotherapy Protocols
ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily G, Member 2
Cyclophosphamide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoadjuvant Therapy

Neoplasm Proteins

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PMID: 33740100
DOI: 10.1007/s00280-021-04244-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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