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Article

Genetic Variations in ABCG2 Gene Predict Breast Carcinoma Susceptibility and Clinical Outcomes after Treatment with Anthracycline-Based Chemotherapy.

BioMed research international - 1 Jan 2015

Wu Huizhe, Liu Yong, Kang Hui, Xiao Qinghuan, Yao Weifan, Zhao Haishan, Wang Enhua, Wei Minjie

Abstract excerpt

The genetic variants of the ATP-binding cassette, subfamily G, member 2 (ABCG2) are known to be involved in developing cancer risk and interindividual differences in chemotherapeutic response. The polymorphisms in ABCG2 gene were genotyped by using PCR-RFLP assays. We found that ABCG2 G34A GA/AA genotype, C421A AA genotype, and haplotypes 34A-421C and 34G-421A were significantly associated with increased risk for...

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Identifiers

PMID: 26634205
DOI: 10.1155/2015/279109
PMCID: PMC4655035

Genes

ABCG2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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