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Article

Novel and recurrent BRCA1/BRCA2 germline mutations in patients with breast/ovarian cancer: a series from the south of Tunisia.

Journal of translational medicine - 16 Mar 2021

Ben Ayed-Guerfali Dorra, Ben Kridis-Rejab Wala, Ammous-Boukhris Nihel, Ayadi Wajdi, Charfi Slim, Khanfir Afef, Sellami-Boudawara Tahia, Frikha Mounir, Daoud Jamel, Mokdad-Gargouri Raja

Abstract excerpt

BACKGROUND: The incidence of breast cancer (BC) and/or ovarian cancer (OC) is increasing in Tunisia especially in young women and mostly those with family history. However, the spectrum of BRCA mutations remains little explored in Tunisian patients in particular in the southern region. METHODS: We sequenced the entire coding regions of BRCA1and BRCA2 genes using next generation sequencing (NGS) in 134 selected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33726785
DOI: 10.1186/s12967-021-02772-y
PMCID: PMC7962399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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