Article
Complete mutation screening and haplotype characterization of BRCA1 gene in Tunisian patients with familial breast cancer.
Cancer biomarkers : section A of Disease markers - 1 Jan 2008
Troudi W, Uhrhammer N, Romdhane K Ben, Sibille C, Amor M Ben, Khodjet El Khil H, Jalabert T, Mahfoudh W, Chouchane L, Ayed F Ben, Bignon Y J, Elgaaied A Ben Ammar
Abstract excerpt
Breast cancer, the most commonly diagnosed cancer in women, is the second leading cause of cancer death in women worldwide. To investigate the contribution of BRCA1 gene mutations to familial breast cancer in Tunisia, 32 unrelated patients who had at least one first degree relative affected with breast and/or ovarian cancer were analysed. BRCA1 mutation analysis was performed by DNA sequencing of all BRCA1 exons....
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