Article
Ethnic Identity and Genome Wide Runs of Homozygosity.
Behavior genetics - 1 Jul 2021
Fieder Martin, Mitchell Brittany L, Gordon Scott, Huber Susanne, Martin Nicholas G
Abstract excerpt
It is long known that inbreeding increases the detrimental effects of recessive sequence variants in "Runs of Homozygosity" (ROHs). However, although the phenotypic association of ROH has been investigated for a variety of traits, the statistical power of the results often remains limited as a sufficiently high number of cases are available for only a restricted number of traits. In the present study, we aim to...
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