Article
Abundance of ethnically biased microsatellites in human gene regions.
PloS one - 1 Jan 2019
Kinney Nick, Kang Lin, Eckstrand Laurel, Pulenthiran Arichanah, Samuel Peter, Anandakrishnan Ramu, Varghese Robin T, Michalak P, Garner Harold R
Abstract excerpt
Microsatellites-a type of short tandem repeat (STR)-have been used for decades as putatively neutral markers to study the genetic structure of diverse human populations. However, recent studies have demonstrated that some microsatellites contribute to gene expression, cis heritability, and phenotype. As a corollary, some microsatellites may contribute to differential gene expression and RNA/protein structure...
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