Article
Runs of homozygosity and distribution of functional variants in the cattle genome.
BMC genomics - 22 Jul 2015
Zhang Qianqian, Guldbrandtsen Bernt, Bosse Mirte, Lund Mogens S, Sahana Goutam
Abstract excerpt
BACKGROUND: Recent developments in sequencing technology have facilitated widespread investigations of genomic variants, including continuous stretches of homozygous genomic regions. For cattle, a large proportion of these runs of homozygosity (ROH) are likely the result of inbreeding due to the accumulation of elite alleles from long-term selective breeding programs. In the present study, ROH were characterized...
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