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Article

Cytopathological features associated with POLE mutation in endometrial cancer.

Cytopathology : official journal of the British Society for Clinical Cytology - 1 May 2023

Yanazume Shintaro, Iwakiri Kaori, Kobayashi Yusuke, Kitazono Ikumi, Akahane Toshiaki, Mizuno Mika, Togami Shinichi, Tanimoto Akihide, Kobayashi Hiroaki

Abstract excerpt

OBJECTIVE: For patients with endometrial cancer, the POLE (polymerase epsilon) mutation (POLEmut)-subtype, one of four molecular-analysis-based categories in the Cancer Genome Atlas (TCGA), has the best prognosis. The following histological characteristics are typically observed in endometroid carcinoma cases with the POLEmut-subtype: (1) the presence of tumour giant cells, (2) numerous tumour-infiltrating...

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PMID: 36727290
DOI: 10.1111/cyt.13215

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Cytopathological features associated with POLE mutation in endometrial cancer.PMID 36727290Read ↗

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