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Article

The impact of common Smurf1 gene variants on the risk, clinical characteristics and short-term prognosis of tuberculous meningitis.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 May 2021

Zhang Meng, He Jian-Qing

Abstract excerpt

OBJECTIVES: Tuberculous meningitis (TBM) is the most severe form of infection caused by Mycobacterium tuberculosis (Mtb). Smurf1 represents a key component in anti-Mtb autophagic targeting in macrophages and in anti-TB host defense in vivo. We hypothesized that genetic variants in the Smurf1 gene region influence susceptibility to TBM. METHODS: Using a case-control study design (235 TBM cases, 239 pulmonary TB...

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PMID: 33711518
DOI: 10.1016/j.ijid.2021.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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