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Article

Common polymorphisms in the CD43 gene region are associated with tuberculosis disease and mortality.

American journal of respiratory cell and molecular biology - 1 Mar 2015

Campo Monica, Randhawa April K, Dunstan Sarah, Farrar Jeremy, Caws Maxine, Bang Nguyen Duc, Lan Nguyen Ngoc, Hong Chau Tran Thi, Horne David J, Thuong Nguyen Thuong, Thwaites Guy E, Hawn Thomas R

Abstract excerpt

CD43, a surface glycoprotein, regulates Mycobacterium tuberculosis macrophage binding, replication, and proinflammatory cytokine induction in a murine model. We hypothesized that single-nucleotide polymorphisms (SNPs) in the CD43 gene region are associated with human tuberculosis (TB) susceptibility. We performed a case-population study in discovery (352 TB cases and 382 control subjects) and validation cohorts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25078322
DOI: 10.1165/rcmb.2014-0114OC
PMCID: PMC4370260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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