Article
Investigation of multidrug-resistance mutations of hepatitis B virus (HBV) in a large cohort of chronic HBV-infected patients with treatment of nucleoside/nucleotide analogs.
Antiviral research - 1 May 2021
Liu Yan, Chen Rongjuan, Liu Wenhui, Si Lanlan, Li Le, Li Xiaodong, Yao Zengtao, Liao Hao, Wang Jun, Li Yuanhua, Zhao Jun, Xu Dongping
Abstract excerpt
Multidrug-resistance hepatitis B virus (MDR HBV), defined as those with mutations resistant to both nucleoside analogs lamivudine/telbivudine/entecavir (LAM/LdT/ETV) and nucleotide analog adefovir (ADV), has potential to cause treatment difficulty. To clarify clinical prevalence and virological features of MDR HBV, we investigated serum samples from 28,236 chronic HBV-infected patients with treatment of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.