Article
Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection.
Antiviral therapy - 1 Jan 2015
Li Xiaodong, Liu Yan, Zhao Pan, Wang Yan, Chen Li, Xin Shaojie, Zhang Xin-Xin, Xu Dongping
Abstract excerpt
BACKGROUND: This study aimed to clarify the clinical significance of drug-resistant HBV in nucleoside/nucleotide analogue (NA)-naive Chinese patients with chronic HBV infection in real clinical practice. METHODS: A total of 845 NA-naive patients who were admitted to Beijing 302 Hospital between July 2007 and March 2012 were included in the study. HBV drug-resistant mutations were examined by direct sequencing of...
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