Article
Trends in hepatitis B virus resistance to nucleoside/nucleotide analogues in North China from 2009-2016: A retrospective study.
International journal of antimicrobial agents - 1 Aug 2018
Guo Xianghua, Wu Jushan, Wei Feili, Ouyang Yabo, Li Qing, Liu Kai, Wang Yanjun, Zhang Yulin, Chen Dexi
Abstract excerpt
Nucleos(t)ide analogues (NAs) are widely used in anti-hepatitis B virus (anti-HBV) therapy for effective inhibition of HBV replication. However, HBV resistance to NAs has emerged, resulting in virus reactivation and disease recurrence. Data on the current dynamics of HBV resistance are still rare in China. This study analysed 4491 plasma samples with HBV primary genotypic resistance mutations representative of...
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