Article
Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations.
World journal of gastroenterology - 21 Sept 2020
Huang Bi-Xia, Liu Yan, Fan Zhen-Ping, Si Lan-Lan, Chen Rong-Juan, Wang Jun, Luo Dan, Wang Fu-Sheng, Xu Dong-Ping, Liu Xin-Guang
Abstract excerpt
BACKGROUND: It is unclear whether immune escape-associated mutations in the major hydrophilic region of hepatitis B virus surface antigen (HBsAg) are associated with nucleoside/nucleotide analog resistance. AIM: To evaluate the association between immune escape-associated mutations and nucleoside/nucleotide analog resistance mutations. METHODS: In total, 19440 patients with chronic hepatitis B virus infection,...
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