Article
Sucrose consumption in mice: major influence of two genetic loci affecting peripheral sensory responses.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 1997
Bachmanov A A, Reed D R, Ninomiya Y, Inoue M, Tordoff M G, Price R A, Beauchamp G K
Abstract excerpt
Individual variability in sucrose consumption is prominent in humans and other species. To investigate the genetic contribution to this complex behavior, we conducted behavioral, electrophysiological, and genetic studies, using male progeny of two inbred mouse strains (C57BL/6ByJ [B6] and 129/J [129]) and their F2 hybrids. Two loci on Chromosome (Chr) 4 were responsible for over 50% of the genetic variability in...
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