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Analysis of Evolution and Ethnic Diversity at Glucose-Associated SNPs of Circadian Clock-Related Loci with Cryptochrome 1, Cryptochrome 2, and Melatonin receptor 1B.

Biochemical genetics - 1 Oct 2021

Yoshiuchi Issei

Abstract excerpt

Diabetes shows high heritability and, worldwide, causes significant health problems including cardiovascular disease and stroke. There is significant variation in the frequency of diabetes between different populations. Both Cryptochromes and Melatonin have a major role to regulate the circadian clock. Circadian clock failure causes metabolic dysfunctions including diabetes and obesity. Variations in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33709300
DOI: 10.1007/s10528-021-10045-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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