Article
MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai.
BMC medical genetics - 14 Apr 2010
Liu Chen, Wu Ying, Li Huaixing, Qi Qibin, Langenberg Claudia, Loos Ruth J F, Lin Xu
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) in White Europeans have shown that genetic variation rs10830963 in melatonin receptor 1B gene (MTNR1B) is associated with fasting glucose and type 2 diabetes, which has also been replicated in several Asian populations. As a variant in the gene involved in the regulation of circadian rhythms, the effect of the variant on sleep status remains unknown. This study...
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