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Article

Demographic history and adaptation account for clock gene diversity in humans.

Heredity - 1 Sept 2016

Dall'Ara I, Ghirotto S, Ingusci S, Bagarolo G, Bertolucci C, Barbujani G

Abstract excerpt

Circadian clocks give rise to daily oscillations in behavior and physiological functions that often anticipate upcoming environmental changes generated by the Earth rotation. In model organisms a relationship exists between several genes affecting the circadian rhythms and latitude. We investigated the allele distributions at 116 000 single-nucleotide polymorphisms (SNPs) of 25 human clock and clock-related genes...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27301334
DOI: 10.1038/hdy.2016.39
PMCID: PMC4981684

Genes

AANAT
FST
NPAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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