Article
Evidence for natural selection at the melanocortin-3 receptor gene in European and African populations.
Acta diabetologica - 1 Aug 2016
Yoshiuchi Issei
Abstract excerpt
AIMS: Obesity is increasing steadily in worldwide prevalence and is known to cause serious health problems in association with type 2 diabetes mellitus (T2DM), including hypertension, stroke, and cardiovascular diseases. According to the thrifty gene hypothesis, the natural selection of obesity-related genes is important during feast and famine because they control body weight and fat levels. Past human...
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