Article
Prediction of Crohn's disease aggression through NOD2/CARD15 gene sequencing in an Australian cohort.
World journal of gastroenterology - 7 May 2014
Bhullar Maneesha, Macrae Finlay, Brown Gregor, Smith Margie, Sharpe Ken
Abstract excerpt
AIM: To investigate the association between mutations in oligomerisation domain 2/caspase recruitment domains 15 (NOD2/CARD15) and the natural history of Crohn's disease (CD) to identify patients who would benefit from early aggressive medical intervention. METHODS: We recruited thirty consecutive unrelated CD patients with a history of ileo-caecal or small bowel resection during the period 1980-2000; Fifteen...
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