Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants

11 Mar 2021

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to PARP inhibition in cancer therapy
Share to Signaling Pathways in Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33705687
DOI: 10.1016/j.chembiol.2021.02.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explantsPMID 33705687Read ↗

PARP inhibitors: New partners in the therapy of cancer and inflammatory diseasesSemantic proximity Read ↗

Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates Macrophage Polarization in Relapsed MelanomaSemantic proximity Read ↗

Integrative multi-omics reveals PARP14 as a key IFNγ-regulated mediator of metastatic progression in Ewing sarcomaSemantic proximity Read ↗

PARP inhibitors enhance antitumor immune responses by triggering pyroptosis via TNF–caspase 8–GSDMD/E axis in ovarian cancerSemantic proximity Read ↗

Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy.Semantic proximity Read ↗

Disruption of macrophage migration inhibitory factor signaling induces major tumor-associated macrophage phenotypes in human M2 macrophages.Semantic proximity Read ↗

A simple method to cure established tumors by inflammatory killing of normal cellsSemantic proximity Read ↗

Cancer cell phagocytosis induces an anti-inflammatory gene regulatory program in macrophagesSemantic proximity Read ↗

p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes.Semantic proximity Read ↗

PGE2-HIF1α reciprocal induction regulates migration, phenotypic alteration and immunosuppressive capacity of macrophages in tumor microenvironment.Semantic proximity Read ↗

Abnormal production of the TNF-homologue APRIL increases the proliferation of human malignant glioblastoma cell lines via a specific receptorSemantic proximity Read ↗

High-throughput heterospheroid-based screening identifies drugs that reprogram tumor-associated macrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.