Article
Circulating Galectin-3 Levels Are Not Associated With Nonalcoholic Fatty Liver Disease: A Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism - 13 Jul 2021
Tremblay Maxime, Perrot Nicolas, Ghodsian Nooshin, Gobeil Émilie, Couture Christian, Mitchell Patricia L, Thériault Sébastien, Arsenault Benoit J
Abstract excerpt
CONTEXT: The impact of galectin-3 inhibitors on nonalcoholic fatty liver diseases (NAFLD)-related outcomes is currently under investigation in randomized clinical trials. Whether there is a causal association between plasma galectin-3 levels and NAFLD is unknown. OBJECTIVE: To evaluate the causal effect of circulating galectin-3 levels on NAFLD as well as >800 other human diseases. DESIGN: Inverse...
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