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Article

Metabolic programs define dysfunctional immune responses in severe COVID-19 patients

26 Feb 2021

Abstract excerpt

It is unclear why some SARS-CoV-2 patients readily resolve infection while others develop severe disease. By interrogating metabolic programs of immune cells in severe and recovered coronavirus disease 2019 (COVID-19) patients compared with other viral infections, we identify a unique population of T cells. These T cells express increased Voltage-Dependent Anion Channel 1 (VDAC1), accompanied by gene programs and...

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PMID: 33691089
DOI: 10.1016/j.celrep.2021.108863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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