Article
Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID.
Cell reports. Medicine - 21 Nov 2023
Wang Kaiming, Khoramjoo Mobin, Srinivasan Karthik, Gordon Paul M K, Mandal Rupasri, Jackson Dana, Sligl Wendy, Grant Maria B, Penninger Josef M, Borchers Christoph H, Wishart David S, Prasad Vinay, Oudit Gavin Y
Abstract excerpt
The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 months following their acute phase of infection to comprehensively profile and assess changes in cytokines, proteome, and metabolome. Network analysis reveals sustained inflammatory response, platelet...
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