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STRide probes: Single-labeled short tandem repeat identification probes.

Biosensors & bioelectronics - 15 May 2021

Tytgat Olivier, Fauvart Maarten, Stakenborg Tim, Deforce Dieter, Van Nieuwerburgh Filip

Abstract excerpt

The demand for forensic DNA profiling at the crime scene or at police stations is increasing. DNA profiling is currently performed in specialized laboratories by PCR amplification of Short Tandem Repeats (STR) followed by amplicon sizing using capillary electrophoresis. The need for bulky equipment to identify alleles after PCR presents a challenge for shifting to a decentralized workflow. We devised a novel...

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PMID: 33690100
DOI: 10.1016/j.bios.2021.113135

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