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Article

Redox Imbalance Associates with Clinical Worsening in Spinocerebellar Ataxia Type 2.

Oxidative medicine and cellular longevity - 1 Jan 2021

Dennis Almaguer-Gotay, Almaguer-Mederos Luis E, Raúl Rodríguez-Aguilera, Roberto Rodríguez-Labrada, Luis Velázquez-Pérez, Dany Cuello-Almarales, Yanetza González-Zaldívar, Yaimeé Vázquez-Mojena, Annelié Estupiñán-Domínguez, Arnoy Peña-Acosta, Reydenis Torres-Vega

Abstract excerpt

BACKGROUND: Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease presenting with redox imbalance. However, the nature and implications of redox imbalance in SCA2 physiopathology have not been fully understood. OBJECTIVE: The objective of this study is to assess the redox imbalance and its association with disease severity in SCA2 mutation carriers. METHODS: A case-control study was conducted...

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Identifiers

PMID: 33688396
DOI: 10.1155/2021/9875639
PMCID: PMC7920744

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