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Molecular Basis for the Interaction of Catalase with D-Penicillamine : Rationalization of some of its Deleterious Effects

2021-09-17

Abstract excerpt

D-penicillamine (D-Pen) is a sulfur compound used in the management of rheumatoid arthritis, Wilson’s disease (WD), and alcohol dependence. Many side effects are associated with its use, particularly after long-term treatment. However, the molecular bases for such side effects are poorly understood. Based on the well-known oxidase activity of hemoproteins, and the participation of catalase in cellular H 2 O 2 re...

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Identifiers and source

Literature Corpus work
5e432e71-f0e6-5855-af60-14c178513ac2
DOI
10.1101/2021.09.16.460603
Open publication

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Molecular Basis for the Interaction of Catalase with D-Penicillamine : Rationalization of some of its Deleterious EffectsDOI 10.1101/2021.09.16.460603
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