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Reduced Level of Serum Thiols in Patients with a Diagnosis of Active Disease

1 Dec 2003

Abstract excerpt

Oxidative stress, or the production of oxygen-centered free radicals, has been hypothesized as the major source of DNA damage that in turn can lead to altered genetic expression, disease, and aging of humans. Serum protein thiol levels in blood are a direct measure of the in vivo reduction/oxidation (redox) status in humans, because thiols react readily with oxygen-containing free radicals to form disulfides....

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PMID: 15142434
DOI: 10.1089/109454503323028920

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