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Article

Quantitative profiling and identification of plasma proteins of spinocerebellar ataxia type 2 patients.

Neuro-degenerative diseases - 1 Jan 2013

Swarup Vishnu, Srivastava Achal K, Padma Madakasira V, Moganty Rajeswari R

Abstract excerpt

BACKGROUND: Spinocerebellar ataxia type 2 (SCA2) is an autosomal-dominant hereditary ataxia characterized by progressive gait and limb ataxia, dysarthria, slow saccades, neuropathy and dementia. The expansion of trinucleotide CAG repeats in the coding region of the ATXN-2 gene leads to expanded polyglutamine stretch in the mutated protein which causes neuronal death. OBJECTIVE: In this study, we investigated the...

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PMID: 23735416
DOI: 10.1159/000346585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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