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Article

Role of the runt‐related transcription factor (RUNX) family in prostate cancer

8 Mar 2021

Abstract excerpt

Prostate cancer (PCa) is a very complex disease that is a major cause of death in men worldwide. Currently, PCa dependence on the androgen receptor (AR) has resulted in use of AR antagonists and antiandrogen therapies that reduce endogenous steroid hormone production. However, within two to three years of receiving first-line androgen deprivation therapy, the majority of patients diagnosed with PCa progress to...

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PMID: 33682350
DOI: 10.1111/febs.15804

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