Article
Prostate cancer expression of runt‐domain transcription factor Runx2, a key regulator of osteoblast differentiation and function
8 May 2003
Abstract excerpt
BACKGROUND: Prostate cancer (CaP) bone metastases express numerous proteins associated with bone cells. Specific transcription factors, including Runx2, regulate the expression of many bone-related factors in osteoblasts. Expression of these transcription factors in CaP may be linked to the ability of CaP bone metastases to influence bone remodeling. METHODS: CaP tissues and cell lines were analyzed for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
