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Identification of long non-coding RNAs in advanced prostate cancer associated with androgen receptor splicing factors

23 Jul 2020

Abstract excerpt

The molecular and cellular mechanisms of development of castration-resistant prostate cancer (CRPC) remain elusive. Here, we analyzed the comprehensive and unbiased expression profiles of both protein-coding and long non-coding RNAs (lncRNAs) using RNA-sequencing to reveal the clinically relevant molecular signatures in CRPC tissues. For protein-coding genes upregulated in CRPC, we found that...

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PMID: 32704143
DOI: 10.1038/s42003-020-01120-y

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