Article
Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2004
Serrano Norma C, Casas Juan P, Díaz Luis A, Páez Carolina, Mesa Clara M, Cifuentes Rodrigo, Monterrosa Alvaro, Bautista Alejandro, Hawe Emma, Hingorani Aroon D, Vallance Patrick, López-Jaramillo Patricio
Abstract excerpt
Polymorphisms in the endothelial NO synthase (eNOS) gene have been evaluated as risk factors for preeclampsia. However, data from small studies are conflicting. We assessed whether eNOS genotypes alter the risk of preeclampsia in a population in which the incidence of this disorder is high. A total of 844 young pregnant women (322 preeclamptic and 522 controls) were recruited from 5 cities. Genotyping for the...
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