X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis.

doi:10.1053/j.gastro.2021.02.061

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Article

X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis.

Gastroenterology - 1 Jun 2021

Asselta Rosanna, Paraboschi Elvezia M, Gerussi Alessio, Cordell Heather J, Mells George F, Sandford Richard N, Jones David E, Nakamura Minoru, Ueno Kazuko, Hitomi Yuki, Kawashima Minae, Nishida Nao, Tokunaga Katsushi, Nagasaki Masao, Tanaka Atsushi, Tang Ruqi, Li Zhiqiang, Shi Yongyong, Liu Xiangdong, Xiong Ma, Hirschfield Gideon, Siminovitch Katherine A, Carbone Marco, Cardamone Giulia, Duga Stefano, Gershwin M Eric, Seldin Michael F, Invernizzi Pietro

Abstract excerpt

BACKGROUND & AIMS: Genome-wide association studies in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually dimorphic complex autoimmune disease. METHODS: We performed a chrX-wide association study, including genotype data from 5 genome-wide association studies (from Italy, United...

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Identifiers

PMID: 33675743
DOI: 10.1053/j.gastro.2021.02.061
PMCID: PMC8169555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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