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Article

POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33

8 Jan 2019

Abstract excerpt

Abstract Primary biliary cholangitis (PBC) is a chronic and cholestatic autoimmune liver disease caused by the destruction of intrahepatic small bile ducts. Our previous genome-wide association study (GWAS) identified six susceptibility loci for PBC. Here, in order to further elucidate the genetic architecture of PBC, a GWAS was performed on an additional independent sample set, then a genome-wide meta-analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30643196
DOI: 10.1038/s41598-018-36490-1

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