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Article

Characteristics of IDH-mutant gliomas with non-canonical IDH mutation.

Journal of neuro-oncology - 1 Jan 2021

Poetsch L, Bronnimann C, Loiseau H, Frénel J S, Siegfried A, Seizeur R, Gauchotte G, Cappellen D, Carpentier C, Figarella-Branger D, Eimer S, Meyronet D, Ducray F

Abstract excerpt

BACKGROUND: Approximately 10% of IDH-mutant gliomas harbour non-canonical IDH mutations (non-p.R132H IDH1 and IDH2 mutations). OBJECTIVE: The aim of this study was to analyse the characteristics of non-canonical IDH-mutant gliomas. MATERIALS AND METHODS: We retrospectively analysed the characteristics of 166 patients with non-canonical IDH mutant gliomas and compared them to those of 155 consecutive patients with...

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PMID: 33205355
DOI: 10.1007/s11060-020-03662-x

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