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A two-tiered targeted proteomics approach to identify pre-diagnostic biomarkers of colorectal cancer risk

4 Mar 2021

Abstract excerpt

Colorectal cancer prognosis is dependent on stage, and measures to improve early detection are urgently needed. Using prospectively collected plasma samples from the population-based Northern Sweden Health and Disease Study, we evaluated protein biomarkers in relation to colorectal cancer risk. Applying a two-tiered approach, we analyzed 160 proteins in matched sequential samples from 58 incident colorectal...

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PMID: 33664295
DOI: 10.1038/s41598-021-83968-6

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