Article
Proteomics for discovery of candidate colorectal cancer biomarkers.
World journal of gastroenterology - 14 Apr 2014
Alvarez-Chaver Paula, Otero-Estévez Olalla, Páez de la Cadena María, Rodríguez-Berrocal Francisco J, Martínez-Zorzano Vicenta S
Abstract excerpt
Colorectal cancer (CRC) is the second most common cause of cancer-related deaths in Europe and other Western countries, mainly due to the lack of well-validated clinically useful biomarkers with enough sensitivity and specificity to detect this disease at early stages. Although it is well known that the pathogenesis of CRC is a progressive accumulation of mutations in multiple genes, much less is known at the...
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